|
|
H2O + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide <=> N-acetyl-D-galactosamine + globotriaosylceramide
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
| |
KEGG:
R05963
|
|
|
|
UDP-N-acetyl-D-galactosamine + globotriosylceramide <=> Globotetraosylceramide + H+ + UDP
|
2.4.1.79
globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
|
–
|
| |
BRENDA:
BS322088;
BS322958
KEGG:
R05631;
R05962
MetaCyc:
2.4.1.79-RXN
|
|
|
|
UDP-galactose + Globotetraosylceramide <=> Galactosylgloboside + H+ + UDP
|
2.4.1
|
–
|
| |
KEGG:
R05964
MetaCyc:
RXN-18298
|
|
|
|
GDP-L-fucose + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer <=> GDP + beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer
|
2.4.1.152
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R05904
|
|
|
|
UDP-N-acetyl-D-glucosamine + Galactosylgloboside <=> UDP + beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer
|
2.4.1
|
–
|
| |
KEGG:
R05902
|
|
|
|
UDP-galactose + lactosylceramide <=> globotriosylceramide + H+ + UDP
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
| |
BRENDA:
BR44202
KEGG:
R03486;
R05960
MetaCyc:
2.4.1.228-RXN
|
|
|
|
UDP-N-acetyl-D-galactosamine + iGb3-Cer <=> UDP + iGb4-Cer
|
2.4.1.79
globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
|
–
|
| |
KEGG:
R11321
|
|
|
|
UDP-galactose + lactosylceramide <=> UDP + iGb3-Cer
|
2.4.1.87
N-acetyllactosaminide 3-alpha-galactosyltransferase
|
–
|
| |
KEGG:
R11320
|
|
|
|
UDP-galactose + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide <=> UDP + IV4-alpha-Gal-Gb4Cer
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
| |
KEGG:
R11376
|
|
|
|
UDP-N-acetyl-D-galactosamine + Globotetraosylceramide <=> GalNAc-alpha-1,3-GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-beta-1,1-ceramide + H+ + UDP
|
2.4.1.88
globoside alpha-N-acetylgalactosaminyltransferase
|
–
|
| |
BRENDA:
BS452152
KEGG:
R04182;
R05965
MetaCyc:
2.4.1.88-RXN
|
|
|
|
UDP-N-acetyl-D-galactosamine + IV4-alpha-Gal-Gb4Cer <=> UDP + NORint
|
2.4.1.79
globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase
|
–
|
| |
KEGG:
R11379
|
|
|
|
globotriosylceramide + H2O <=> lactosylceramide + D-galactose
|
3.2.1.22
alpha-galactosidase
3.2.1.47
galactosylgalactosylglucosylceramidase
|
–
–
|
| |
BRENDA:
BR16005
KEGG:
R03618;
R05961
MetaCyc:
3.2.1.47-RXN
|
|
|
|
CMP-N-acetylneuraminate + Galactosylgloboside <=> monosialylgalactosylgloboside + CMP + H+
|
2.4.99.4
beta-galactoside alpha-2,3-sialyltransferase
|
–
|
| |
KEGG:
R05967
MetaCyc:
RXN-18299
|
|
|
|
GDP-L-fucose + Galactosylgloboside <=> Globo-H + GDP + H+
|
2.4.1
2.4.1.69
type 1 galactoside alpha-(1,2)-fucosyltransferase
|
–
–
|
| |
KEGG:
R05968
MetaCyc:
RXN-18300
|
|
|
|
GalNAc-alpha-1,3-GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-beta-1,1-ceramide + H2O <=> N-acetyl-D-galactosamine + beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide
|
3.2.1.49
alpha-N-acetylgalactosaminidase
|
–
|
| |
BRENDA:
BR22665
KEGG:
R04183;
R05966
SABIO-RK:
3901
|
|
|
|
UDP-galactose + NORint <=> UDP + NOR2_antigen
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
| |
KEGG:
R11377
|
|
|
|
UDP-N-acetyl-D-galactosamine + iGb4-Cer <=> UDP + alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer
|
2.4.1.88
globoside alpha-N-acetylgalactosaminyltransferase
|
–
|
| |
KEGG:
R11322
|
|
|
|
UDP-galactose + beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer
|
2.4.1
|
–
|
| |
KEGG:
R05903
|
|
